Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs748448196
rs748448196
ZNF644
0.010 GeneticVariation BEFREE Myopia disease mouse models: a missense point mutation (S673G) and a protein-truncating mutation of the <i>Zfp644</i> mimic human disease phenotype. 30834109

2019
dbSNP: rs1554208945
rs1554208945
ZNF292
C 0.700 GeneticVariation CLINVAR

dbSNP: rs869422
rs869422
ZMAT4
0.700 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965

2016
dbSNP: rs13382811
rs13382811
ZEB2
0.020 GeneticVariation BEFREE The association between either of these two SNPs alone and myopia did not replicate significantly in the combined cohorts of European descent, providing only suggestive results (<i>p</i><sub>allelic</sub> = 0.0088 for rs13382811 and <i>p</i><sub>allelic</sub> = 0.0319 for rs6469937). 28848321

2017
dbSNP: rs13382811
rs13382811
ZEB2
0.020 GeneticVariation BEFREE The risk allele T of <i>ZC3H11B</i> SNP rs4373767 was significantly associated with high myopia (OR=1.39, p=0.007) and extreme myopia (OR=1.34, p=0.013) when compared with controls, whereas <i>ZFHX1B</i> rs13382811 (allele T, OR=1.33, p=0.018) and <i>SNTB1</i> rs7839488 (allele G, OR=1.71, p=8.44E-05) were significantly associated with extreme myopia only. 31300455

2019
dbSNP: rs10453441
rs10453441
WNT7B
0.020 GeneticVariation BEFREE We identify WNT7B as a novel susceptibility gene for axial length (rs10453441, Pmeta=3.9 × 10(-13)) and corneal curvature (Pmeta=2.9 × 10(-40)) and confirm the previously reported association between GJD2 and myopia. 25823570

2015
dbSNP: rs10453441
rs10453441
WNT7B
0.020 GeneticVariation BEFREE WNT7B SNPs located in the same genomic region that includes rs9330813 have previously been associated with CCT in Latinos but with other ocular quantitative traits related to myopia (corneal curvature and axial length) in a Japanese population (rs10453441 and rs200329677). 29847655

2018
dbSNP: rs200329677
rs200329677
WNT7B
0.010 GeneticVariation BEFREE WNT7B SNPs located in the same genomic region that includes rs9330813 have previously been associated with CCT in Latinos but with other ocular quantitative traits related to myopia (corneal curvature and axial length) in a Japanese population (rs10453441 and rs200329677). 29847655

2018
dbSNP: rs9330813
rs9330813
WNT7B
0.010 GeneticVariation BEFREE WNT7B SNPs located in the same genomic region that includes rs9330813 have previously been associated with CCT in Latinos but with other ocular quantitative traits related to myopia (corneal curvature and axial length) in a Japanese population (rs10453441 and rs200329677). 29847655

2018
dbSNP: rs2010963
rs2010963
VEGFA
0.010 GeneticVariation BEFREE This association was successfully replicated in the additional 76 eyes with myopic CNV, and pooled analysis revealed significant association of rs2010963 with CNV size (P = 0.00078). 22427559

2012
dbSNP: rs2853559
rs2853559
VDR
0.010 GeneticVariation BEFREE One SNP within VDR was significantly associated with myopia in the multivariate analysis of the primary sample (rs2853559: odds ratio = 1.99, P = 0.003). 21357399

2011
dbSNP: rs876657731
rs876657731
USH2A ; LOC102723833
T 0.700 CausalMutation CLINVAR

dbSNP: rs2839471
rs2839471
UMODL1
0.010 GeneticVariation BEFREE We did not find evidence for the association of myopia with rs577948, rs11218544, or rs2839471 in the Chinese population studied. 22194655

2011
dbSNP: rs28940881
rs28940881
TYR ; LOC107984363
G 0.700 CausalMutation CLINVAR

dbSNP: rs61754381
rs61754381
TYR ; LOC107984363
A 0.700 CausalMutation CLINVAR

dbSNP: rs1327062642
rs1327062642
TULP1
TG 0.700 CausalMutation CLINVAR Antioxidant effect of aqueous extract of four plants with therapeutic potential on gynecological diseases; Semen persicae, Leonurus cardiaca, Hedyotis diffusa, and Curcuma zedoaria. 29178942

2017
dbSNP: rs543860009
rs543860009
TTN ; TTN-AS1
A 0.700 CausalMutation CLINVAR

dbSNP: rs878854378
rs878854378
TTN ; TTN-AS1
A 0.700 GeneticVariation CLINVAR

dbSNP: rs866294686
rs866294686
TRIM8 ; LOC105378460
T 0.700 GeneticVariation CLINVAR

dbSNP: rs1331463984
rs1331463984
TRAF7
A 0.700 CausalMutation CLINVAR

dbSNP: rs11145488
rs11145488
TJP2
0.700 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965

2016
dbSNP: rs826220
rs826220
THRB
0.700 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965

2016
dbSNP: rs111854391
rs111854391
TGFBR1
T 0.700 CausalMutation CLINVAR

dbSNP: rs2207136
rs2207136
TFAP2B
0.700 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965

2016
dbSNP: rs56299331
rs56299331
TCF7L2
0.700 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965

2016